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Page 1
SERVICE MANUAL Automated Blood Coagulation Analyzer CA-500 Section 1 Specifications Section 2 Hydraulics and Mechanics Section 3 Electronics Section 4 Adjustment Section 5 Service Program Section 6 Error Messages and Troubleshooting Section 7 Schematics Appendix A Parts List Appendix B… -
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2 Woodlands Sector 1, #01-06, Woodlands Spectrum Singapore 738068 TELEPHONE: 65-221-3629 FAX: 65-221-3687 Copyright © 1999 through 2001 by SYSMEX CORPORATION First Edition November 1999 Second Edition December 2001 All right reserved. No part of this book may be reproduced in any form or by any electronic or mechanical means, including information storage and retrieval systems, without written permission from the publisher. -
Page 3: Table Of Contents
Performance, Intended Use and Effectiveness ………………1-3 1.4.1 Intended Use ………………………1-3 1.4.2 Performance……………………..1-3 1.4.3 Functions……………………..1-9 Acoustic Noise Level ……………………..1-13 Environmental Conditions……………………1-14 1.6.1 Operating Environment ………………….1-14 1.6.2 Reagents to be used ………………….1-14 How to Operate ……………………..1-15 CA-500 Series S/M Revised December 2001…
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Page 4: Section 1 Specifications
SECTION 1 SPECIFICATIONS OUTLINE The Sysmex CA-500 Automated Blood Coagulation Analyzer obtains clotting times by detecting changes in scattered light intensity reflected from a diluted sample with buffer reagent which are illuminated by red light of LED. Incubated plasma taken from the centrifuged sample blood is rapidly mixed with warmed reagent and coagulation is performed and analyzed.
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Page 5: Power Source
Controls Main Unit system. (11) Drive Circuit Unit Controls each motor ‘s driving. (12) Pneumatic Unit (13) Sampler Unit Enables the continuous automatic operations by the sampler. One sampler rack can contain 10 sample tubes. CA-500 Series S/M Revised December 2001…
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Page 6: Principles Of Measurement
(b) Activation Percent (for European and UK specifications only) [% ] Fibrinogen (Fbg) [second] Calculated Parameters: (a) Fibrinogen Concentration [mg/dL] Thrombo Test (Plasma Method) [second] Calculated Parameters: (a) Activation Percent (b) INR (for European and UK specification only) [ – ] CA-500 Series S/M Revised December 2001…
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Page 7
4) Plasma FDP (CA-550 and CA-560 only) With applicable reagents, measuring is possible from 2.5 to 480 µg/mL. However, in the concentration of 60 µg/mL or above, measurement is performed in 8-hold dilution mode (+PFC). CA-500 Series S/M Revised December 2001… -
Page 8
AT-III CV within 5% CV within 5% CV within 5% BCPC CV within 5% [IU/mL] CV within 5% SFDP [µg/mL] CV within 10% PFDP [µg/mL] CV within 10% D-Dimmer [µg/L] [µg/mL] CV within 10% CA-500 Series S/M Revised December 2001… -
Page 9
( Measurement at rated voltage ) PT, APTT (second) ± 8% or less Fbg, TTO, HpT (second) ± 10% or less AT III (%) ± 10% or less D-Dimmer (µg/L) ± 10% or less CA-500 Series S/M Revised December 2001… -
Page 10
CA-Series Comlex Factor TTO Citrated Plasma Owren’s Veronal buffer CA-Series Complex Factor HPT Citrated Plasma Owren’s Veronal buffer II, V, YII, X Citrated Plasma Owren’s Veronal buffer Factor Deficient Plasma (Continues to the next page.) CA-500 Series S/M Revised December 2001… -
Page 11
Latex Test BL-2 P-FDP Diluent Latex Test BL-2 P-FDP Latex P-FDP Diluent Additionally, approximately 6 mL of distilled water and approximately 212 µL (at the maximum) of rinsing solution (CA CLEAN I) are required for rinsing per test. CA-500 Series S/M Revised December 2001… -
Page 12: Functions
The analyzer has the function to allow setting additional samples to the rack in process after starting a measurement and measuring them. The registration of the additional samples can be made on the left side from the left-end tube position for the samples already set in rack and registered for measurement. CA-500 Series S/M Revised December 2001…
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Page 13
Pipette is rinsed by controlling the syringe and the solenoid valve, with applying the pressure on the Rinse Bottle. 4) Waste Draining: The waste is aspirated by controlling the solenoid valve, with applying vacuum on the waste bottle. CA-500 Series S/M 1-10 Revised December 2001… -
Page 14
(vii) Error messages (viii) Maintenance information and various setting values (ix) Temperatures at incubation well, heater pipette, reagent cooler unit Input Method Change, select, and set functions on each screen by LCD touch panel method. CA-500 Series S/M 1-11 Revised December 2001… -
Page 15
5) Service Function For the Customer: Displaying of standard curve data and setting of abnormal values (range) For the Servicing Personnel: Service mode, System tests, Memory Initialization, and adjustment/setting (of X-Y axis position) CA-500 Series S/M 1-12 Revised December 2001… -
Page 16: Acoustic Noise Level
(2) Measuring operation status: 60 dB or less Temporary noises (less than 65 dB continued within 5 seconds) are produced on occasions, such as home positioning of X-Y table or syringe drive mechanism are not included. CA-500 Series S/M 1-13 Revised December 2001…
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Page 17: Environmental Conditions
Control Plasma P(Human) DadeCi-Trol Coagulation Control,Level 1 DadeCi-Trol Coagulation Control,Level 2 DadeCi-Trol Coagulation Control,Level 3 Standard Human Plasma P-FDP Standard D-Dimer PLUS Standard Plasma PT Calibration Plasma Kit CA CLEAN Ⅰ CA CLEAN Ⅱ CA-500 Series S/M 1-14 Revised December 2001…
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Page 18: How To Operate
• The analysis results will be displayed on LCD and printed out on printer paper. End Analysis • Remove the reagents and the sample. Shutdown • Execute the daily maintenance for the next analysis. Power OFF • Rinse the pipette and turn the instrument power OFF. CA-500 Series S/M 1-15 Revised December 2001…
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Page 19
Assembly Diagram ……………………2-9 BAR CODE READER UNIT (ID COMPLETED PARTS) …………..2-10 2.9.1 Outline ……………………..2-10 2.9.2 Specifications/Functions………………….2-10 2.10 PUMP UNIT (PRESSURE PUMP/VACUUM PUMP COMPLETED PARTS) ……..2-11 2.10.1 Outline ……………………..2-11 2.10.2 Specifications/Functions………………….2-11 2.10.3 Assembly Diagram ………………….2-11 CA-500 Series S/M Revised December 2001… -
Page 20: Tubing Diagram
Si4: Tube Silicone 6 x 10 TF1: Tube Teflon 1.2 x 2.0 TF2: Tube Teflon 1.5 x 2.5 Tube Toalone 3 x 6 Connecting Tube No. 50 Connecting Tube No. 3 Nipple No. 123 CA-500 Series S/M Revised December 2001…
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Page 21: Hydraulic System Operation
When draining, the probe moves to the reaction tube in the Reaction Tube Rack to dispense, the volumetric syringe ascends and dispenses the sample. After that, the probe moves to home position, and moves to the Probe Rinse Cup (inside). CA-500 Series S/M Revised December 2001…
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Page 22
Next, the probe moves to the Probe Rinse Cup (outside), and both the Probe Rinse Cup (outside) valve and the valve on probe open to rinse the probe. After rinsing, the probe returns to the home position. CA-500 Series S/M Revised December 2001… -
Page 23: Pressure Circuit
Pressure Pump Pump type: Drive power supply: AC 100 V, 50/60 Hz Pressure generation: Over 300 g/cm Vacuum Pump Pump type: Drive power supply: AC 100 V, 50/60 Hz Vacuum generation: Over -100 g/cm CA-500 Series S/M Revised December 2001…
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Page 24: Detector Block
DETECTOR BLOCK 2.4.1 Outline The CA-500 detector block is provided with 4 scattered light detecting ports, 1 transmitted light detecting port, and 6 incubation wells. The detector block is kept at 37°C by the heater and the semiconductor temperature sensor.
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Page 25: Reagent Cooling Unit
To cold-store reagents, electronic cooling element (Peltier element) cools the 4-hole reagent set. 2.5.2 Specifications/Functions Cooling source: Peltier element (1 piece, DC 12 V applied) Cooling: 1 unit of DC fan and fin-type radiator Temperature detection: Semiconductor temperature sensor — 1 unit 2.5.3 Assembly Diagram CA-500 Series S/M Revised December 2001…
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Page 26: Volumetric Unit
Sensor: For drive unit home position (transmission type) — 1 unit Syringe System Piston diameter: 3 mm Vertical stroke: Approx. 21 mm Approx. 151 µL/21 mm Syringe volume: Life: 300,000 cycles 2.6.3 Assembly Diagram CA-500 Series S/M Revised December 2001…
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Page 27: Outline
Drive transmission: Timing belt type Resolving power: Approx. 0.08 mm/step Drive speed: Approx. 4000 pps (at high speed in trapezoidal control) Sensor: For drive unit home position (transmission type) — 1 unit 2.7.3 Assembly Diagram CA-500 Series S/M Revised December 2001…
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Page 28: Outline
Sensor: Detects presence of reaction tubes (modulation-reflection type) — 1 unit (4) Sample Probe Shape⋅Material: ID 0.50 mm/OD 0.85 mm, SUS316 Heater: Sensor: Glass chip thermistor Overheat protection: Thermal fuse 76°C 2.8.3 Assembly Diagram CA-500 Series S/M Revised December 2001…
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Page 29: Bar Code Reader Unit (Id Completed Parts)
Read Width: 80 mm Scan Cycles: 500 scans/500 decodes per second Interface: Conforms to RS-232C Power Source: DC 5 V, 300 mA Corresponding Code: CODE39, NW-7, Industrial 2 of 5, CODE 128, etc. CA-500 Series S/M 2-10 Revised December 2001…
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Page 30: Pump Unit (Pressure Pump/Vacuum Pump Completed Parts)
2.10.2 Specifications/Functions (1) Pressure Pump Structure: Pressure: 250 mmHg as adjusted (2) Vacuum Pump Structure: Vacuum: Approx. 180 mmHg as not adjusted 2.10.3 Assembly Diagram CA-500 Series S/M 2-11 Revised February 2004 TB200408…
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Page 31
3.14 PCB No. 9264 (Z RELAY; Z-Axis Relay, Z-Axis Home Position Sensor)……….3-25 3.15 PCB No. 9265 (PR RELAY; Operation Panel, Syringe Motor, SV 1 Relay) ……….3-26 PCB No. 9303 (PR RELAY2; Operation Panel, Syringe Motor, SV 1 Relay) ………..3-26 CA-500 Series S/M Revised December 2001… -
Page 32: Section 3 Electronics
Z-Axis Relay, Z-Axis Home Position Sensor PCB No. 9265 PR RELAY Operation Panel, Syringe Motor, SV Relay PCB No. 9303* PR RELAY2 NOTE: PCB No. indicated with (*) is added with CA-550/560 which is upper compatible. CA-500 Series S/M Revised December 2001…
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Page 33: Block Diagram And Power Source
Motor Drive Waste Sampler Bottle Sample Rack Sensor Sampler Table RS232C ID Unit Drive Motor ID Unit Sensor (Option) Serial Port ID Unit Table Lock Home Pos. Sensor Figure 3-2a: CA-500 Electric Block Diagram 1 CA-500 Series S/M Revised December 2001…
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Page 34
Motor Drive Waste Sampler Bottle Sample Rack Sensor Sampler Table ID Unit RS232C ID Unit Drive Motor Sensor (Option) Serial Port ID Unit Table Lock Home Pos. Sensor Figure 3-2b: CA-500 Electric Block Diagram 2 CA-500 Series S/M Revised December 2001… -
Page 35
3.2.2 Power Supply System CA-500 Power Supply System is composed of the Power Transformer, Switching Regulators and PCB No. 4086 as shown in the following figure. (Respective voltages indicated with balloon numbers are explained in the descriptions.) Figure 3-3: CA-500 Power Supply System Block Diagram… -
Page 36
Power Supply Board PCB No. 4086 P + 5 V: For Built-in Printer power source DC ± 15 V: For Analog Circuit power source (via PCB No. 6362, 2132, 2134, 9260) CA-500 Series S/M Revised December 2001… -
Page 37: Pcb No. 2132 (Pd; Photo Diode, Pre-Amplifier, Led Relay)
PCB No. 2156 (2 Circuits Coag) 662-0282-6 1,3,5 PCB No. 2132 (3 Circuits) CA-530/540/550/560 662-0219-1 PCB No. 2156 (3 Circuits 662-0283-0 Chrom/Immuno) <Detector Block> 3.3.2 Block Diagram Figure 3-4: PCB No. 2132 and 2156 Block Diagram CA-500 Series S/M Revised December 2001…
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Page 38
ON/OFF. R23~R26 bleeds only to turn LED for CH6. 3.3.4 Setting and Adjustment Setting and adjustments are not necessary. 3.3.5 LED and Test Point There is no LED and Test Points. 3.3.6 Assembly Drawing Figure 3-5: PCB No. 2132 Assembly Drawing CA-500 Series S/M Revised December 2001… -
Page 39: Pcb No. 2133 (Thermo; Thermister)
(3) Probe Arm Y-Axis Home Position Sensor (4) Probe Arm Y-Axis Motor Signal Line Relay (5) Relay to PCB No. 9264 (Z RELAY) 3.5.2 Block Diagram Figure 3-6: PCB No. 2134 and 2157 Block Diagram CA-500 Series S/M Revised December 2001…
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Page 40
Probe crash is monitored by a micro-switch in the probe holder (normally ON). The micro-switch turns OFF when probe is pushed back and the probe crash signal is generated. The probe crash signal is latched by flip-flop. 3.5.4 Settings and Adjustment Setting and adjustments are not necessary. CA-500 Series S/M Revised December 2001… -
Page 41
3.5.6 Assembly Drawing Figure 3-7: PCB No. 2134 Assembly Drawing CA-500 Series S/M 3-10 Revised December 2001… -
Page 42: Pcb No. 4086 (Ps; Power Source, Motor Driver)
TA8415, TD62308 • Solenoid Valve TD62308 • Probe Heater, Detector Block Heater, Peltier Cooler Power MOSFET • Sampler Table Lock, Mixing Motor Transistor with resistor • Vacuum, Pressure Pump (AC Photo coupler) TLP3503 CA-500 Series S/M 3-11 Revised December 2001…
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Page 43
PCB No. 6373 (MAIN-2) w/registor) Probe heater +24V from PCB No. 6362 (MAIN) ON/OFF to Probe heater from PCB No. 6373 (MAIN-2) Driver Figure 3-8-a: PCB No. 4086 Block Diagram (to be continued) CA-500 Series S/M 3-12 Revised December 2001… -
Page 44
3.6.4 Setting and Adjustment Setting and adjustments are not necessary. Refer to Section 4 to verify each voltage. 3.6.5 LED and Test Point (1) LED No LED is used. (2) Test Point TP1: CA-500 Series S/M 3-13 Revised December 2001… -
Page 45
3.6.6 Assembly Drawing Figure 3-9: PCB No. 4086 Assembly Drawing CA-500 Series S/M 3-14 Revised December 2001… -
Page 46: Pcb No. 6350 (Prcn-1; Printer Control Board)
Phase A, B Motor Most Significant Address Motor Driver Address Latch Time Monitor to 8 bit data cut off the power Latch LATCH DATA Reset CLOCK clock Figure 3-10: PCB No. 6350 and 6375Block Diagram CA-500 Series S/M 3-15 Revised December 2001…
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Page 47: Pcb No. 6362 (Main; Cpu, I/O, Motor Control, Temperature Control, A/D)
(17) Temperature Control Circuit (18) Pressure Control Circuit (19) Stepper Motor Control (20) Vacuum Pump Drive (21) SV Control, Sampler Table Lock Control (22) Buzzer Control (23) Mixing Motor Control (24) Bus Interface CA-500 Series S/M 3-16 Revised February 2004 TB200408…
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Page 48
3.8.2 Block Diagram Figure 3-11: PCB No. 6362 and 6373 Block Diagram CA-500 Series S/M 3-17 Revised December 2001… -
Page 49
The negative voltage of the LCD drive is created from + 5 V by the DC-DC Converter (U704). For the contrast signal, the voltage divided from the above negative voltage by the external volume PCB No. 9263 (VR) is supplied to LCD. CA-500 Series S/M 3-18 Revised December 2001… -
Page 50
Rack Switch, the Sample Table Switch, the Rinse Bottle Sensor, the Waste Bottle Sensor, and the Tube Catch Sensor are activated. (15) DIP SW Entry (SW202, U207) Among the 9 bits of the Dip Switch, the 1 ~ 8 bits can be used as port entries. CA-500 Series S/M 3-19 Revised December 2001… -
Page 51
Additionally, as the signals other than the signals of Detector Block, +5 V, +24 V voltage level signals and the pressure sensor signal are entered, which enables the voltage monitoring and the pressure indication. Figure 3-12: Detector Block Interface CA-500 Series S/M 3-20 Revised December 2001… -
Page 52
In the case the pressure decreases in this circuit, the signal activating the pressure pump is output. The other comparator circuit and the latch circuit (U519, 520, 521) are used for detecting the pressure error. Figure 3-14: Pressure Control Circuit CA-500 Series S/M 3-21 Revised December 2001… -
Page 53
4086 is controlled by this VR101. (24) Bus Interface This circuit is composed by the Address Bus, the Data Bus, the Address Decoder (U203, 203, 205, 206, etc.), and the RD/WR signal generating circuit (U208). CA-500 Series S/M 3-22 Revised December 2001… -
Page 54: Pcb No. 7015 (Memory; Program Memory)
On this memory card, the flash memory is directly connected to the connector of the card. This is not a PC card, therefore, do not insert it to the card slot on the instrument other than CA-500. 3.9.2 Setting and Adjustment Setting and adjustments are not necessary.
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Page 55: Pcb No. 9259 (Led1; Led For Transmitted Light)
Figure 3-16: PCB No. 9260 Block Diagram 3.12.3 Settings and Adjustment Setting and adjustments are not necessary. 3.12.4 LED and Test Point There are no LEDs or test point. 3.12.5 Assembly Drawing Figure 3-17: PCB No. 9260 Assembly Drawing CA-500 Series S/M 3-24 Revised December 2001…
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Page 56: Pcb No. 9263 (Vr; Lcd Contrast Volume)
Figure 3-18: PCB No. 9264 Block Diagram 3.14.3 Setting and Adjustment Setting and adjustments are not necessary. 3.14.4 LED and Test Point There are no LEDs or test point. 3.14.5 Assembly Drawing Figure 3-19: PCB No. 9264 Assembly Drawing CA-500 Series S/M 3-25 Revised December 2001…
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Page 57: Pcb No. 9265 (Pr Relay; Operation Panel, Syringe Motor, Sv 1 Relay)
Figure 3-20: PCB No. 9265 and 9303 Block Diagram 3.15.3 Setting and Adjustment Setting and adjustments are not necessary. 3.15.4 LED and Test Point There are no LEDs or test point. 3.15.5 Assembly Drawing Figure 3-21: PCB No. 9265 Assembly Drawing CA-500 Series S/M 3-26 Revised December 2001…
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Page 58
PCB No. 6362: MAIN (CPU, I/O, Motor Control, Temperature Control, A/D) ……32 PCB No. 6373: MAIN-2 (CPU, I/O, Motor Control, Temperature Control, A/D)……. 32 4.5.2 PCB No. 4086: PS (Power Source, Motor Driver) …………..34 CA-500 Series S/M Revised December 2001… -
Page 59: Section 4 Adjustment
Figure 4-1-1: Rear View Adjustment procedure: 1) Turn the power OFF. Remove the rear panel and the dummy cover under the HOST connector. Figure 4-1-2: Dummy Cover (Left Side View) CA-500 Series S/M Revised December 2001…
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Page 60
13) Verify that pressure is 250 ± 3 g/cm * If pressure is not 250 ± 3 g/cm , check and adjust again by repeating Steps 1) to 5). Figure 4-1-3: PCB No. 6362 Jumper, VR Location CA-500 Series S/M Revised December 2001… -
Page 61: Adjustment Of Pressure Indication
Adjust the gain value by using [+] and [-] keys so that the pressure gauge value (adjusted 250 g/cm by the procedure described in 4.1.1 Adjustment of Pressure Detector Circuit) agrees with the displayed pressure value on CA-500. The difference between the pressure gauge value and CA-500 displayed value should be adjusted within 3 g/cm Verify Steps 3) to
again, and if the value is within the specified range.
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Page 62: Detector Block Sensitivity Adjustment
3) Press [Sensitive] key to alternate the sensitivity of the selected channel in the order of High Gain Low Gain PT Gain. 4) Start the automatic adjustment for the offset/gain value by pressing [Auto Adjust] key. CA-500 Series S/M Revised December 2001…
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Page 63
2) Instruments with new main board (PCB NO.6373) are able to switch off LEDs during standby operation automatically in order to prolong the life time of the LEDs. CA-500 Series S/M Revised May 2003 ECR 303C012… -
Page 64: Adjustment Of Detector Well For Analyzing The Scattered Light
[Gain] position by pressing [ ] or [ ] key. 4) Press [Auto Adjust] key to start the automatic gain adjustment, and when the adjustment is completed, the alarm sounds. 5) Execute Steps 1) to 5) for channels 2 to 4. CA-500 Series S/M Revised December 2001…
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Page 65
The gain adjustment and the offset adjustment have an influence on each other, therefore, reconfirm that the set value after each adjustment is within the specified range of values. Refer to 5.9.2 Detector Block Adjustment Value for default value. CA-500 Series S/M Revised December 2001… -
Page 66: Adjustment Of Detector Well For Analyzing The Transmitted Light (Chromogenic And Immunoassy)
If the A/D value exceeds 4,000, set the reaction tube at the position where the indicated A/D value is the biggest and press [Auto Adjust] key again to start the adjustment. 6) Execute Steps 1) to 5) for channel 6. CA-500 Series S/M Revised December 2001…
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Page 67: Exit Adjustment
480 ± 15 480 ± 15 – – GAIN 910* Scattering Stick 910 ± 20 – – – – Distilled Water – – – 3800 — 4000 3800 — 4000 *Varies lot by lot. CA-500 Series S/M 4-9-1 Revised February 2004 TB200408…
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Page 68
Press [Cancel] key to return to the LED Calibration Update Confirmation screen. Press [OK] key to save the new adjustment value, and return to Calibration screen. Take out the calibrator for the calibration, and set the former reagent. CA-500 Series S/M 4-9-2 Revised May 2003… -
Page 69: Mechanical System Adjustment
The screen changes from “Main Menu” to “Mecha Position” by pressing keys of [Special Operate] [Service] [Adjust] [Mecha Position]. Select the unit to be adjusted on this screen and perform the position adjustment. CA-500 Series S/M 4-10 Revised May 2003 ECR 303C012…
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Page 70: The Mechanical System Position Adjustment Screen
(12) [XY TEST] Key: Move XY drive according to the setting pulses. When the probe is not at the home position, it will move to the setting value after returning to the home position. CA-500 Series S/M 4-11 Revised December 2001…
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Page 71
Fine Adjustment (Individual position) Mode: Set each position for 29 points. Basic Position Adjustment Mode: Set the basic position for each block. By this setting, the accompanying position within the block can be set automatically. Detection Well Immunoassy [CH6] Figure 4-3-2: Table Positions CA-500 Series S/M 4-12 Revised December 2001… -
Page 72: Position Adjustment Procedure Of Pipette («[1]Blood 1», «[2]Blood 10», And «[3]Blood_Stat»)
Verify that the “[1] blood 1” is shown on the left center of the screen. If not, change to “[1] blood 1” by using [Pos. -] and [Pos. +] keys. Move the pipette to the setting position by using [XY TEST] key. CA-500 Series S/M 4-13 Revised December 2001…
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Page 73
10) Press [Pos. +] key to select the setting position “[2]blood 10”. 11) Execute Steps 3) to 8). 12) Move the sample cup to the blood_stat position. 13) Press [Pos. +] key to select the setting position “[3]blood_stat”. 14) Execute Steps 3) to 8). CA-500 Series S/M 4-14 Revised December 2001… -
Page 74
Mecha. Position Adjustment screen. Be sure to press [Enter] key to set the value. When pressing [FIX] key, 25 pulses are added to Z pulse setting value and the value is automatically set as the pipette lower limit. CA-500 Series S/M 4-15 Revised December 2001… -
Page 75: Position Adjustment Procedure Of Pipette («[4]Reag 1») («[5]Reag 9») («[6]Reag 10»)
Section 4.3.4: Position Adjustment Procedure of Pipette, (3) Pipette Lower Limit Adjustment when it stops before detecting liquid surface. Set “650” pulse for the pipette lower limit of the reagent rack. CA-500 Series S/M 4-16 Revised December 2001…
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Page 76: Position Adjustment Procedure Of Pipette («[7]Reag_Rinse») («[8] Buffer»)
7) Press [Z TEST] key again to ascend and descend the pipette. Verify that the pipette is placed at the center of the sample cup.
Press [XY ORG] key to return the pipette (head) to the home position. 9) Adjust “[8]buffer” in the same way CA-500 Series S/M 4-17 Revised December 2001…
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Page 77
Section 4.3.4: Position Adjustment Procedure of Pipette, (3) Pipette Lower Limit Adjustment when it stops before detecting liquid surface. Set “650” pulse for the pipette lower limit of the reagent rack. Adjust “[8]buffer” in the same way. CA-500 Series S/M 4-18-1 Revised December 2001… -
Page 78
3) Press [Set] to carry out Auto Z-axis Position Adjustment. 4) Press [Return] [Fix] to save parameters. When ‘Single’ is selected, Z position adjustment at each of R1 to R10 can be performed individually. CA-500 Series S/M 4-18-2 Revised May 2003… -
Page 79: Position Adjustment Procedure Of Pipette («[10]Wash_O)
Press [Z TEST] key again to ascend and descend the pipette. Verify that the pipette is placed at the center of the sample cup. Figure 4-3-13: Probe Rinse Cup (Outside) Press [XY ORG] key to return the pipette (head) to the home position. CA-500 Series S/M 4-19 Revised December 2001…
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Page 80
[Enter Pulses] key. Probe Rinse Cup (Inside) Value [9]wash-i setting value X value Same as Probe Rinse Cup (Outside)Value Y value Probe Rinse Cup (Outside)Value + 200 Z value Same as Probe Rinse Cup (Outside)Value CA-500 Series S/M 4-20 Revised December 2001… -
Page 81
CAUTION: 1) Do not execute Z operation when XY adjustment is insufficient. 2) Be sure that the pipette tip is at the center of the reaction tube. If not, it may cause the pipette to touch the reaction tube when descended. CA-500 Series S/M 4-21 Revised December 2001… -
Page 82
6) Press [Tube Free] and [Tube Catch] keys to release and catch the reaction tube. Y direction: Use [ ] and [ ] keys to adjust the center of the reaction tube agrees the center of the catcher. Figure 4-3-17: Y Direction Adjustment CA-500 Series S/M 4-22 Revised December 2001… -
Page 83
9) When completed, press [XY ORG] key to return the catcher to the home position. 10) Setting Position: [18]c_tube 5, [19]c_tube 26, [20]c_tube 31, [21]c_tube 35, [22]c_tube 56 Adjust above 5 positions in the same way. CA-500 Series S/M 4-23 Revised December 2001… -
Page 84
6) Press [Tube Free] and [Tube Catch] keys to release and catch the reaction tube. (a) Y direction: Use [ ] and [ ] keys to adjust the center of the reaction tube agrees the center of the catcher. Figure 4-3-20: Y Direction Adjustment CA-500 Series S/M 4-24 Revised December 2001… -
Page 85
This is the X adjustment value. When completed, press [XY ORG] key to return the catcher to the home position. 10) Setting Position: [24]warm 3, [25]warm 4, [26]comp, Adjust above 3 positions in the same way. CA-500 Series S/M 4-25 Revised December 2001… -
Page 86
Figure 4-3-24: Catcher Adjustment 7) Press [XY ORG] key to return the pipette to the home position. CAUTION: DO NOT press [Z ORG], [Z TEST] or [Z ADJUST] key. That will cause pipette crash. CA-500 Series S/M 4-26 Revised December 2001… -
Page 87
9) Use [Tube Free] and [Tube Catch] keys to verify that the reaction tube to enter smoothly into the reaction tube trash. 10) When the adjustment is completed, press [XY ORG] key to return pipette (head) to the home position. CA-500 Series S/M 4-27 Revised December 2001… -
Page 88
[Z ADJUST] key. Adjust the reaction tube position in X direction to touch the left part of the inner wall of the immunoassay well by repeating this operation. Figure 4-3-27: X Direction Adjustment CA-500 Series S/M 4-28 Revised December 2001… -
Page 89: Output Setting Values
Press [Return] or [Quit] key on the right bottom of the screen to display the confirmation screen as follows: Figure 4-3-27: Confirmation Screen Press [FIX] key to update the setting value and then output. CA-500 Series S/M 4-29 Revised December 2001…
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Page 90: Temperature Adjustment
4.4.2.1 Cooling section (Reagent Cooler) After 30 minutes since turning power ON of CA-500, perform the following procedures. 1) Pour 4 mL of distilled water into DADE 1 mL bottle, and put it into position No.4 of reagent rack. 2) Measure temperature of the water, and confirm that temperature is within 15.0 +/-2°C.
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Page 91: Temperature Adjustment Procedures
Press [Clear] key returns the cursor positioned value before it is changed, which is stored in EEPROM. It will be stored in the memory by pressing [FIX] key when exiting the Temp. Control screen. CA-500 Series S/M 4-31 Revised December 2001…
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Page 92: Electrical Adjustment
1) Connect the voltmeter between TP101 and the frame (GND). 2) Adjust VR101 so that the voltage when rotating the mixing motor becomes 1.05 ± 0.02 V. 3) Fix VR101 with paint lock. CA-500 Series S/M 4-32 Revised December 2001…
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Page 93
Verify Pressure Sensor Analog Output 4.5.1.3 Assembly Drawing TP202 TP201 MAIN DP0173C D403 D401 D402 NOZ. DET. COL. VR502 VR501 VR101 CN104 CN101 TP501 TP101 TP503 TP401 TP402 TP502 Figure 4-5-1: PCB No. 6362 Assembly Drawing CA-500 Series S/M 4-33 Revised December 2001… -
Page 94: Pcb No. 4086: Ps (Power Source, Motor Driver)
Make sure that the voltage on each switching regulator and PS Board (PCB No. 4086) shows the output voltage in Table below. (There is no adjusting point.) Turn the power switch of the CA-500 Main Unit OFF and connect CN101, CN104 on Main Board (PCB No. 6362) with CN2 on PCN1 (PCB No. 6350).
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Page 95
5.11.11 Customer Setting Value …………………. 5-29 5.11.12 Standard Curve Settings………………… 5-32 5.11.13 Quality Control • Setting Value ………………. 5-33 5.11.14 Analysis Parameter Default Setting Value…………….5-34 5.12 Settings of CA-500 with 800nm detector ………………5-36 CA-500 Series S/M Revised October 2003… -
Page 96: Section 5 Service Program
Drain Liquid Dispense Volume Flag Threshold Full Power Reagent Temp. Test Mode Tube Transfer Test Catcher Test Reag. Vial Settings Print Service Set. Service Setting Flag Threshold Test Mode Reag. Vial Settings CA-500 Series S/M Revised May 2003 ECR 303C012…
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Page 97: Service Setting
Cancels the renewed setting and returns to the Service Menu screen. [FIX]: Changes to the renewed setting and returns to the Service Menu screen. (Setting data will be stored in the memory.) [Continue]: Returns to the Service Setting screen and allows continuous operation. CA-500 Series S/M Revised December 2001…
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Page 98
No test protocols will be displayed in the test setting screen. • No reagents will be displayed in the reagent name setting screen. • The settings will not be initialized by using “Init. Settings-1” and “Init. Entire Memory” on the “Initial” menu. CA-500 Series S/M Revised July 2003… -
Page 99: Adjust
1485 2 HIGH 2265 1246 warm3 1469 06/17/1999 11:22 -356 TEMP warm4 COOLER Main -356 comp DETECT Main -369 shake PIPETTE Main dust ROOM Main -376 Figure 5-3-2: Example of Setting Data Print Out CA-500 Series S/M Revised December 2001…
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Page 100: Initialize
(1) Press [Int. Stored Data] key, then the confirmation screen will appear. (2) Press the appropriate key. [Set]: To start stored data initializing. When completing, the “Initial” screen will appear. [Cancel]: To cancel stored data initializing, and return to the “Initial” screen. CA-500 Series S/M Revised December 2001…
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Page 101: Initializing Qc Data
[Cancel]: To cancel entire memory initializing, and return to the “Initial” screen. NOTE: By setting the DIP SW 202 — Bit 6 on PCB No. 6362 to ON position, the BBRAM settings are cleared automatically at power ON. CA-500 Series S/M Revised December 2001…
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Page 102: Initializing Service Settings
(3) Flag for error message “Turned Off During Operation”. Syringe operation cycle counts Test counts (4) Group selection number Rinse Wait time (Clean Sample Probe) Catcher transfer test cycle counts Catcher transfer test error cycle counts Storing dummy range CA-500 Series S/M Revised December 2001…
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Page 103: Contents Stored In Eeprom
Ensuring the dummy range 5.4.9 Items needing backup when initializing The following items are required the backup (printing out) when replacing PCB No.6362. (1) EEPROM All data excluding fixed data. (2) BBRAM Group selection number Rinsing time CA-500 Series S/M Revised December 2001…
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Page 104: Test Menu
Figure 5-5-2: Drain Liquid Confirmation Screen Water Drain Process 1 This process discards the liquid in the Rinsing bottle, then select the appropriate key. CAUTION: Be careful when opening the rinsing bottle as it is pressurized. CA-500 Series S/M Revised December 2001…
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Page 105: Dispense Volume
Press [Set] key to perform the dispensing operation. After dispensing, measure the test sample by the electric balance. If dispensed volume is OK, press [Quit] key. Then the screen will return to the Test Menu display. CA-500 Series S/M 5-10 Revised December 2001…
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Page 106: Full Power
(3) To cancel power consumption test operation Press [Return] key to stop the operation, then the power consumption test setting screen will appear. (This program does not stop automatically. You must press [Return] key when you stop this program.) CA-500 Series S/M 5-11 Revised December 2001…
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Page 107: Reagent Temp
[Tube Trans Test] keys to start, then the following screen will be displayed. Ready Sysmex Replace Rack? YES! Tube Trans Test Tube No. = 1 Warm No. = 1 Detect No. = 1 Return Figure 5-5-6: Tube Transfer Test Screen CA-500 Series S/M 5-12 Revised February 2004 TB200408…
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Page 108: Catcher Test
[Return] key: Press to quit the test and to return to Test Menu display. (3) To cancel catcher test operation Press [Cancel] key to stop the operation, then the catcher test setting screen will appear. CA-500 Series S/M 5-13 Revised December 2001…
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Page 109: Flag Threshold
Calibration a: The slant of calibration. Calibration b: The segment of calibration. High Accurate Dilute ratio The parameter for dilute ratio of standard curve analysis. ON: accuracy equal to the CA-1500 OFF: conventional accuracy CA-500 Series S/M 5-14 Revised December 2001…
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Page 110
[Print] Key Use to output the settings for all tests to the built-in printer. Numeric Keys When the cursor is moved to each setting value, numeric keys appear as below to input the value. CA-500 Series S/M 5-15 Revised December 2001… -
Page 111
Cancels the renewed setting and returns to the Service Menu screen. [FIX]: Changes to the renewed setting and returns to the Service Menu screen. [Continue]: Returns to the Service Setting screen and allows continuous operation. CA-500 Series S/M 5-16 Revised December 2001… -
Page 112: Test Mode
Below 7 sec. APTT: Below 15 sec. 5.7.2 Rinse Wait Time Set the time period to leave the rinse solution within pipette during manual pipette rinsing. Time between 1 and 600 seconds can be set. CA-500 Series S/M 5-17 Revised December 2001…
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Page 113: Barcode Mod. 7
This setting is used for the factory use only. Used OFF: Not used 5.7.6 Vlin interim (For Factory Use Only) This setting is used for the factory use only. Used OFF: Not used CA-500 Series S/M 5-18 Revised December 2001…
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Page 114: Reagent Vial Setting
Use to change the selected item by displaying [Next Option] key or numeric keys. [Z Pulse Down] Key Use to move to the descend pulse adjustment screen. [Return] or Key Returns to Reagent Vial setting screen. CA-500 Series S/M 5-19 Revised December 2001…
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Page 115
(3) The probe moves to the reagent holder No. 9 and detect a liquid surface for 5 times. (4) The difference between the average of the descend pulse and the value of the reagent holder No. 9 position adjustment will be calculated as the pulse correction value. CA-500 Series S/M 5-20 Revised December 2001… -
Page 116: Output Of Service Settings
Use to output the test mode values. [Reag. Vial Settings] Key Use to output the reagent vial setting values. [Return] or [Quit] Key Quits to output service settings and returns to Service Menu screen. CA-500 Series S/M 5-21 Revised December 2001…
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Page 117: Led Calibration Setting
Warning Limit (DA) Error Limit (DA) Enter Next Next Option Quit Figure 5-10-2: LED Calibration Setting Screen [ ] and [ ] Keys Use to move cursor. The selected item is displayed in reversed. CA-500 Series S/M 5-22 Revised December 2001…
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Page 118: Adjustment Value Calculation Method
When there are 3 or more data of the setting value, the mean value, without a maximum and minimum data, will be calculated and becomes as the adjustment value. If there are 2 or less data, the mean value of all becomes as the adjustment value. CA-500 Series S/M 5-23 Revised December 2001…
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Page 119: Factory Setting Value Table
Incubation Well 3 1469 -356 Incubation Well 4 -356 Chrom. Well -369 Immuno Well 1347 -369 Others Position Reagent Dispense Discard Well -376 (3) Barcode (Fixed) Position Tube 1 Tube 10 2308 STAT CA-500 Series S/M 5-24 Revised December 2001…
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Page 120: Detector Block Adjustment Value
Pressure Adjustment Value Offset Gain NOTE: These are the displayed values when initialized. In case of initializing the EEPROM, refer to the values labeled on the CPU board. Refer to Section 4.1 Pressure Adjustment. CA-500 Series S/M 5-25 Revised December 2001…
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Page 121: Service Setting Value
SLD Vial 45.357 5.11.9 LED Calibration Value LED Calibration Total Volume (/tube) Adjustment Cycle Dispensing Volume (/tube) Warning Limit (DA) Aspiration Speed Error Limit (DA) Dispensing speed CV Limit CV Check Reaction tube number CA-500 Series S/M 5-26 Revised December 2001…
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Page 122: Analysis Protocol
(4) TT Sample Aspiration 100 µL First Reagent 120 sec Reagent volume 9 TT 50 µL Rinse 11 50 µL Detection Activity-others Coag. detection point Sensitivity Low Sensitivity Max. detection time 190 sec CA-500 Series S/M 5-27 Revised December 2001…
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Page 123
Coag. start point 11 sec Coag. end point 40 sec Sensitivity Low Sensitivity There is a case that (4) TT — (7) AT-III are not set. It depends on the Service Settings. NOTE: CA-500 Series S/M 5-28 Revised December 2001… -
Page 124: Customer Setting Value
AT-III (2) Reagent volume monitor Inactivate. (3) Test name APTT AT-III (4) Reagent name AT3.T APTT AT3.S CaCl Rinse2 Rinse Buffer (5) Reagent Holder AT3.T APTT AT3.S Cacl2 Rinse2 Rinse ReagVial Buffer ReagVial CA-500 Series S/M 5-29 Revised December 2001…
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Page 125
AT-III (8) Fbg Limits Upper Limit Lower Limit Unit 50.0 475.0 mg/dL (9) Replication Limits APTT AT-III (10) Report Limit < > Unit 130.0 APTT 15.0 320.0 25.0 950.0 mg/dL 110.0 AT-III 125.0 CA-500 Series S/M 5-30 Revised December 2001… -
Page 126
When CA-1000 format is selected, a sample ID number up to 13 digits is used. NOTE: When CA-500 format is selected, a sample ID number up to 15 digits is used. Note that when the sample ID number consists of 15 characters and CA-1000 format is used, the upper 2 digits are automatically deleted. -
Page 127: Standard Curve Settings
Digit Calculation Method 1 Valid TTO% XXX.X Log-Log point plotted graph 2 Invalid XX.XX 3 Invalid XX.XX 4 Invalid Auto Dilution Analysis 150, 100, 50, 25, 12.5, 0 % analysis times: 3 times CA-500 Series S/M 5-32 Revised December 2001…
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Page 128: Quality Control • Setting Value
5.11.13 Quality Control • Setting Value (a) All parameters Analysis Time Once Analysis Stop Cond. Upper Limit Upper Limit Target Lower Limit Analysis Stop Cond. Lower Limit Expire Date 2000/00/00 (b) Judging parameters APTT mg/dL AT-III CA-500 Series S/M 5-33 Revised December 2001…
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Page 130
0.0000 0.0000 0.0000 Lower Preevaluation Rate 0.1000 0.1000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 Min. Regression Time Mixing Time for Sample Mixing Time for Reagent Calibration a Calibration b High Accurate Dilute Ratio CA-500 Series S/M 5-35 Revised December 2001… -
Page 131: Settings Of Ca-500 With 800Nm Detector
5.12 SETTINGS OF CA-500 WITH 800NM DETECTOR When settings of CA-500 with 800nm detector are initialized, the settings of CA-500 with 575nm detector are applied. Therefore following settings must be changed to recover it. (1) Service setting 1) Press [Special Menu]-[Special Operate]-[Service]-[Service Setting].
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Page 132
Load New Sample ……………………26 Analysis Errors……………………….27 6.7.1 Analysis Error ……………………..27 6.7.2 Check Reagent Expiry …………………..28 6.7.3 Check Control Expiry …………………….28 Memory Errors……………………….29 6.8.1 Invalid Settings ……………………..29 6.8.2 Stored Data Error……………………29 6.8.3 QC Data Error……………………..29 CA-500 Series S/M Revised December 2001… -
Page 133
6.11.2 Turned Off During Operation …………………37 6.11.3 Light Shield Open ……………………37 6.11.4 Enter Work List ……………………..38 6.11.5 Check Reagent Volume 1………………….38 6.11.6 Insufficient Reaction Tube ………………….38 6.12 Others…………………………39 6.12.1 Voltage Low Limit ……………………39 6.12.2 CPU Failure (“Number”) ………………….40 CA-500 Series S/M Revised December 2001… -
Page 134
Light Shield Open ………………………..37 Load New Sample………………………..26 No Paper…………………………..30 No Reaction Tube………………………..17 No Sample (Rack Position)……………………..14 Pressure Pump Error ……………………….1 Printer Error …………………………31 Probe Crash…………………………18 QC Data Error …………………………29 QC Limit Error…………………………34 QC Limit Error (STOP)……………………….34 CA-500 Series S/M Revised December 2001… -
Page 135
Vacuum Pump Error ……………………….2 Voltage Low Limit…………………………39 Waste Bottle is full …………………………7 X Axis Home Position Error ……………………..8 Y Axis Home Position Error ……………………..9 Z Axis Down Error………………………..11 Z Axis Home Position Error ……………………..10 CA-500 Series S/M Revised December 2001… -
Page 136: Section 6 Error Message
Measure voltage at the connector of pump by the DVM. If AC 100 V ± 15% is displayed, the pump is failed; if not, the drive circuit is failed. 141V peak -141V peak Figure 6-1-1: Normal Oscilloscope Wave CA-500 Series S/M Revised December 2001…
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Page 137: Vacuum Pump Error
If AC 100 V ± 15% is displayed when the pump is operating, the pump is failed; if not, the drive circuit is failed. 3. Vacuum pump only operates when rinse cup liquid draining. Check the voltage in this timing. CA-500 Series S/M Revised December 2001…
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Page 138: Temperature Errors
PCB No. 6362 CN105 pin 8 and pin 9 on PCB No. 6362 3 K to 4 K PCB No. 4086 CN14 pin 15 and pin 16 on PCB No. 4086 10 K to 20 K CA-500 Series S/M Revised December 2001…
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Page 139: Temperature Error (High)/Detector, Temperature Error (Low)/Detector
CN8 (PCB No. 4086) pin 1 and pin 5 below 3 or over 7 NOTE: Use high input impedance device. Usually normal Digital Volt Meter input impedance is higher than 1 Mega and Oscilloscope is higher than 10 Mega . CA-500 Series S/M Revised December 2001…
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Page 140: Temperature Error (High)/Cooler, Temperature Error (Low)/Cooler
12 V ±10% When the voltage between pin 4 and 5 of CN8 (PCB No. 4086) shows 12 V, the harness of Peltier heater unit is failed. Otherwise, the PCB No. 4086 is failed. CA-500 Series S/M Revised December 2001…
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Page 141: Temperature Error (High)/Room, Temperature Error (Low)/Room
1. Confirm temperature by checking temperature displayed on the main unit. Confirmation by Service Engineer 1. Confirm temperature by checking temperature displayed on the main unit. 2. When the temperature is not displayed or 99.9 °C is displayed, the PCB No. 6362 is failed. CA-500 Series S/M Revised December 2001…
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Page 142: Chamber Errors
1. Replenish rinse solution. 2. Securely connect the float switch connector. Confirmation by Service Engineer 1. If an error can be solved by the short-circuiting 2-pin connector on the rear panel, the float switch is failed. CA-500 Series S/M Revised December 2001…
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Page 143: Motor Errors
Turn the pulley by hand. If it does not move, the motor or drive mechanism is faulty. Failure of the drive mechanism a) Check for flaws on the shaft. b) If the shaft is free from flaws, the problem is in the bushing. CA-500 Series S/M Revised December 2001…
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Page 144: Y Axis Home Position Error
Turn the pulley by hand. If it does not move, the motor or drive mechanism is faulty. 4. Failure of the drive mechanism a) Check for flaws on the shaft. b) If the shaft is free from flaws, the problem is in the bushing. CA-500 Series S/M Revised December 2001…
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Page 145: Z Axis Home Position Error
Turn the pulley by hand. If it does not move, the motor or drive mechanism is faulty. 4. Failure of drive mechanism a) Check for flaws on the shaft. b) If the shaft is free from flaws, the problem is in the bushing. CA-500 Series S/M 6-10 Revised December 2001…
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Page 146: Z Axis Down Error
Any of motor, PCB No. 9264, PCB No. 2134, X-axis wiring cord, and PCB No. 4086 is faulty. Replace and confirm. Failure of drive mechanism Check for flaws on the shaft. If the shaft is free from flaws, the problem is in the bushing. CA-500 Series S/M 6-11 Revised December 2001…
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Page 147: Tube Catch Error (Position)
CN1 (PCB No. 9260) pin 16 (GND) and pin 4 0 V when a tube is detected CN105 (PCB No. 6362) pin 13 (GND) and 0 V when a tube is detected pin 1 CA-500 Series S/M 6-12 Revised December 2001…
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Page 148: Tube Release Error (Position)
CN1 (PCB No. 9260) pin 16 (GND) and pin 4 0 V when a tube is detected CN105 (PCB No. 6362) pin 13 (GND) and pin 1 0 V when a tube is detected CA-500 Series S/M 6-13 Revised December 2001…
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Page 149: Dispensing Errors
CN1 (PCB No. 9260) pin 16 (GND) and pin 5 5 V when probe touches liquid surface CN105 (PCB No. 6362) pin 13 (GND) and pin 5 V when probe touches liquid surface CA-500 Series S/M 6-14 Revised December 2001…
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Page 150: Sampling Error (Position)
1. Check whether a sample location (rack number) matches its registration or not. 2. Secure the frame grounding of the power supply. Confirmation by service Engineer. 1. Failure of PCB No. 2134 2. Always secure frame grounding in a noisy environment. CA-500 Series S/M 6-15 Revised December 2001…
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Page 151: Insufficient Reagent (Holder No.)
CN1 (PCB No. 9260) pin 16 (GND) and pin 5 5 V when probe touches liquid surface CN105 (PCB No. 6362) pin 13 (GND) and pin 5 V when probe touches liquid surface CA-500 Series S/M 6-16 Revised December 2001…
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Page 152: No Reaction Tube
CN1 (PCB No. 9260) pin 16 (GND) and pin 4 0 V when a tube is detected CN105 (PCB No. 6362) pin 13 (GND) and pin 1 0 V when a tube is detected CA-500 Series S/M 6-17 Revised December 2001…
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Page 153: Probe Crash
CN105 (PCB No. 6362) pin 13 (GND) and pin 0 V when probe crash occurs * PCB No. 2134 latches Crash signal each time. So, confirm the above by pressing the liquid level sensor reset switch in the service mode. CA-500 Series S/M 6-18 Revised December 2001…
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Page 154: Syringe Error
Check for flaws on the shaft. b) If the axis is free from flaws, check the bushing is all right or not. c) Check the piston No. 28 is broken or not. CA-500 Series S/M 6-19 Revised December 2001…
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Page 155: Check Syringe Unit
Confirmation by the operator None Confirmation by Service Engineer 1. If the warning is displayed in the normal status, replace the syringe. 2. In other case, the PCB No. 6362 might be faulty. CA-500 Series S/M 6-20 Revised December 2001…
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Page 156: Sampler Errors
3. If the above step 2 does not solve the trouble, short-circuit the pin 14 and pin 12 of CN111 on PCB No. 6362. If this solves the trouble, the wiring cord (wiring cord with spiral) is faulty. If not, the PCB No. 6362 is faulty. CA-500 Series S/M 6-21 Revised December 2001…
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Page 157: Replace Sample Rack Drawer
4. If the above step 3 does not solve the trouble, short-circuit the pin 5 and pin 6 of CN112 on PCB No. 6362. If this solves the trouble, the wiring cord (wiring cord from CN19 on PCB No. 4086) is faulty. If not, the PCB No. 6362 is faulty. CA-500 Series S/M 6-22 Revised December 2001…
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Page 158: Barcode Scanner Driver Error
3. Failure of wiring cord (wiring cord with spiral) 4. Failure of PCB No. 6362 Confirmation by the operator None Confirmation by Service Engineer Replace and confirm. Otherwise, confirm connections and identify failed locations by a voltmeter. CA-500 Series S/M 6-23 Revised December 2001…
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Page 159: Change Sample Rack
6. If the above step 5 does not solve the trouble, short-circuit the pin 5 and pin 6 of CN112 on PCB No. 6362. If this solves the trouble, the wiring cord (wiring cord from CN19 on PCB No. 4086) is faulty. If not, the PCB No. 6362 is faulty. CA-500 Series S/M 6-24 Revised December 2001…
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Page 160: Replace Stat Sample
4. If the above step 3 does not solve the trouble, short-circuit the pin 5 and pin 6 of CN112 on PCB No. 6362. If this solves the trouble, the wiring cord (wiring cord from CN19 on PCB No. 4086) is faulty. If not, the PCB No. 6362 is faulty. CA-500 Series S/M 6-25 Revised December 2001…
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Page 161: Exist Same Sample No
1. New rack is not loaded when the analysis is re-started after adding new order. Confirmation by the operator 1. Check sample rack. 2. Check sample table Confirmation by Service Engineer 1. Check the sample rack sensor. CA-500 Series S/M 6-26 Revised December 2001…
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Page 162: Analysis Errors
Antigen became range over (with Reanalyze the sample by re-dilution, etc. (Range Over) Immunoassy only). ERROR0528 Polynomial adjustment could not Check the setting, reagent and reanalyze. (No Polynomial be performed (when using Adjustment) VlinIntegral mode only). CA-500 Series S/M 6-27 Revised December 2001…
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Page 163: Check Reagent Expiry
Probable Cause 1. Failure to preset expiry date of control plasma or wrong setting Confirmation by the operator 1. Preset expiry date properly at QC settings. Confirmation by Service Engineer The same as above. CA-500 Series S/M 6-28 Revised December 2001…
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Page 164: Memory Errors
Probable Cause Refer to below (3). Confirmation by the operator 1. Turn the power switch off, and on again. Confirmation by Service Engineer 1. The PCB No. 6362 or backup battery is faulty. CA-500 Series S/M 6-29 Revised December 2001…
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Page 165: External Device Errors
CN1 (PCB No. 6350) pin 15 and pin 1 0 V when probe crash occurs PCB No. 6362 CN106 (PCB No. 6362) pin 15 and pin 1 0 V when probe crash occurs CA-500 Series S/M 6-30 Revised December 2001…
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Page 166: Printer Error
Confirmation by the operator 1. Check the connection with host computer. 2. Turn on the host computer. 3. Check the host computer data transmission. Confirmation by Service Engineer 1. Replace the PCB No. 6362. CA-500 Series S/M 6-31 Revised December 2001…
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Page 167: Hc Communication Error
2. Failure of host computer 3. Failure of PCB No. 6362 Confirmation by The operator 1. Check the connection with host computer. 2. Check the host computer. Confirmation by Service Engineer 1. Replace the PCB No. 6362. CA-500 Series S/M 6-32 Revised December 2001…
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Page 168: Hc Ack Time Out
2. Problem is occurred on the program of the host computer. Confirmation by the operator 1. Register the Work List in the host computer correctly. Confirmation by Service Engineer The same as above (2). CA-500 Series S/M 6-33 Revised December 2001…
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Page 169: Quality Control And Standard Curve Errors
1. The number of point of standard curve is not satisfied on actual analysis. Confirmation by the operator 1. Preset more than two points. Confirmation by Service Engineer The same as above (2). CA-500 Series S/M 6-34 Revised December 2001…
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Page 170: Standard Curve Error
Warning Probable Cause 1. Data of Standard Curve is out of limit. Confirmation by the operator 1. Preset the correct data of Standard Curve Confirmation by Service Engineer The same as above (2). CA-500 Series S/M 6-35 Revised December 2001…
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Page 171: Operation Errors
CN107 (PCB No. 6362) pin 9 and pin 10 5 V ± 0.25 V, when the mechanical (for printer relaying) stop switch is ON 0 V, when the mechanical stop switch is not ON Figure 6-3: Mechanical Switch ON CA-500 Series S/M 6-36 Revised December 2001…
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Page 172: Turned Off During Operation
5 V ± 0.25 V, when light shield cover is OPEN Wiring Cord CN112 (PCB No. 6362) pin 8 and pin 9 Does not change the signal when light (wiring cord from CN19 shield is OPEN or CLOSED or PCB No. 4086) CA-500 Series S/M 6-37 Revised December 2001…
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Page 173: Enter Work List
1. The number of test registered in Work List exceeds that of the remaining reaction tubes (a maximum of 60 tests). Confirmation by the operator 1. Reduce the number of test registered in Work List. 2. Replenish the reaction tube. Confirmation by Service Engineer The same as above (2). CA-500 Series S/M 6-38 Revised December 2001…
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Page 174: Others
• PCB No. 9260 • X axis motor wiring cord • PCB No. 2134 • Y-Z relay harness • PCB No. 9264 • Y axis motor • Z axis motor • Reagent heater pipette CA-500 Series S/M 6-39 Revised December 2001…
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Page 175: Cpu Failure («Number»)
1. Main program failure of PCB No. 7015 Confirmation by the operator 1. Turn the power OFF/ON. 2. Contact your Sysmex service representative. Confirmation by Service Engineer No. 3, 4, 5, 97, 256 1. Check the data check operation of the service program.
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Page 176
To Cover SECTION 7 SCHEMATICS CA-500 WIRING/TUBING DIAGRAM………………….7-1 CA-500 Series S/M Revised December 2001… -
Page 177
Moter Drive DC12V CN4 CN5 CN6 Built-in CN13 SW Reg. Printer Touch Key Contrast DC5V Adjust. VR CN12 FUSE AC100V Power SW PCBNO.9236 Waste CN10 Invertor AC100V AC+/-16.5V CN15 Emergency Switch Stop SW CN18 PCBNO.9265 PCBNO.9303 CA-500 Wiring/Tubing Diagram TB200408… -
Page 178
APPENDIX A PARTS LIST To Cover Contents Page CA-500 Main Unit Chassis Assy (1/2) …………….. A-1-2 CA-500 Main unit Chassis Assy (2/2) ……………… A-1-4 CA-500 Chassis Assy (1/2)………………..A-1-6 CA-500 Chassis Assy (2/2)………………..A-1-8 CA-500 Detector Block …………………. A-1-10 CA-500 Cooling Section Assy……………….. A-1-12 Table Lock Mech. -
Page 179: Main Unit Chassis Assy (1/2
CA-500 Main Unit Chassis Assy (1/2) CA-500 Series S/M A-1-2 Revised December 2001…
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Page 180
CA-500 MAIN UNIT CHASSIS ASSY (1/2) Code No. Drawing No. Description Qty per Unit 663-0202-5 REAGENT STAGE ASSY 663-0203-9 2& SAMPLE STAGE ASSY 663-0400-9 SAMPLE STAGE ASSY 2 (IMMUNO) 663-0168-5 OPERATION PANEL ASSY 663-0174-8 SAMPLE TABLE ASSY (ID) 663-0173-4 SAMPLE TABLE ASSY (STANDARD) -
Page 181: Main Unit Chassis Assy (2/2
CA-500 Main unit Chassis Assy (2/2) CA-500 Series S/M A-1-4 Revised December 2003 ECR303K033…
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Page 182
CA-500 Main unit Chassis Assy (2/2) Code No. Drawing No. Description Qty per Unit 442-5475-1 TUBE TOALONE 3MMID X 6MMOD 442-5315-1 TUBE SILICONE 2MMIDX5MMOD(CLR) 442-1403-8 CONNECTING TUBE NO. 3 442-5290-6 TUBE SILICONE 4MMID X 8MMOD 266-5045-0 5$¥ FUSE 125V6A UL-TSC-6A-N1 266-5106-0 5$¥… -
Page 183: Chassis Assy (1/2
CA-500 Chassis Assy (1/2) Details of Part D Details of Part C Details of Part B CA-500 Series S/M A-1-6 Revised June 2003 ECR303C033…
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Page 184
CA-500 Main unit Chassis Assy (2/2) Code No. Drawing Description Qty per Unit 663-0180-1 DRIVE ARM ASSY 662-0223-6 PCB NO.2134 662-0286-1 2*#& PCB NO.2157 663-0181-4 X AXIS SLIDER ASSY 663-0374-9 BASE DM1197B 663-0371-8 SHAFT-B DM1090B A 14 663-0370-4 PULLEY 1329A… -
Page 185: Chassis Assy (2/2
CA-500 Chassis Assy (2/2) CA-500 Series S/M A-1-8 Revised December 2001…
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Page 186
CA-500 Chassis Assy (2/2) Code No. Drawing Description Qty per Unit 663-0161-0 COOLING SECTION ASSY 663-0217-1 TABLE LOCK MECHANISM ASSY 663-0199-1 RINSING CUP ASSY 663-0158-8 DETECTOR BLOCK (AT3) 663-0159-1 DETECTOR BLOCK (STANDARD) 663-0399-1 4& DETECTOR BLOCK (D-DIMER) 663-0415-4 4&& DETECTOR BLOCK (D-DIMER 800NM) -
Page 187: Detector Block
CA-500 Detector Block CA-500 Series S/M A-1-10 Revised December 2001…
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Page 188
CA-500 Detector Block Code No. Drawing Description Qty per Unit 663-0159-1 1-5* DETECTOR BLOCK (STANDARD) 663-0158-8 1-6# DETECTOR BLOCK (AT3) 663-0399-1 1-8& DETECTOR BLOCK (D-DIMER) 663-0415-4 1-8$ DETECTOR BLOCK (D-DIMER 800NM) 662-0217-3 PCB NO.2132 (STANDARD) 662-0281-2 PCB NO.2156 (STANDARD CLOT/AT3) 662-0285-7 1&… -
Page 189: Cooling Section Assy
CA-500 Cooling Section Assy CA-500 Series S/M A-1-12 Revised June 2003 ECR303C033…
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Page 190
CA-500 Cooling Section Assy Code No. Drawing Description Qty per Unit 663-0161-0 COOLING SECTION ASSY 663-0162-3 COOLER ASSY (THERMAL MODULE) 663-0163-7 COOLING FAN ASSY 662-2206-0 COOLER THERMAL ASSY (SERNSOR IC) 426-3152-0 SILICONE GREASE THERMAL 800-8 348-5936-2 SCREW ROUND M3X15 PC(+) -
Page 191: Axis Slider Assy
Table Lock Mech. Assy X AXIS SLIDER ASSY CA-500 Series S/M A-1-14 Revised December 2001…
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Page 192
TABLE LOCK MECHANISM ASSY & X AXIS SLIDER ASSY Code No. Drawing Description Qty per Unit 663-0217-1 TABLE LOCK MECHANISM ASSY 663-0200-8 SOLENOID ASSY 228-3753-3 PHOTO-INTERRUPTER LG-217D-3 663-0181-4 X AXIS SLIDER ASSY 663-0185-9 Y AXIS MOTOR ASSY 342-1816-4 TIMING BELT B488MXL9.5 CA-500 Series S/M A-1-15 Revised December 2001… -
Page 193: Z Axis Base Assy
CA-500 Z Axis Base Assy CA-500 Series S/M A-1-16 Revised March 2003 303A066 200049…
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Page 194
CA-500 Z Axis Base Assy Code No. Drawing Description Qty per Unit 663-0182-8 Z AXIS BASE ASSY 663-0183-1 PIPETTE HOLDER ASSY 663-0188-0 CATCHER ASSY 663-0186-2 Z AXIS MOTOR ASSY 662-0222-2 PCB NO.9264 228-4050-8 PHOTO-IC SENSOR PS-R11L 663-0189-3 TUBING ASSY (PIPETTE) -
Page 195: Catcher Assy
CA-500 Catcher Assy CA-500 Pipette Holder Assy CA-500 Series S/M A-1-18 Revised December 2001…
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Page 196
CA-500 CATCHER ASSY & PIPETTE HOLDER ASSY Code No. Drawing Description Qty per Unit 663-0188-0 CATCHER ASSY 345-3767-8 SPRING PIN KSSC 2017 663-0187-6 MIXER MOTOR ASSY 346-4213-1 O-RING S-3 (SLICONE) 324-9077-1 VIBRATION ARM DM1163 324-9082-0 C ARM PLATE DM1221 324-9081-6… -
Page 197: Volumetric Piston Assy
CA-500 Volumetric Piston Assy CA-500 Cylinder Assy CA-500 Series S/M A-1-20 Revised December 2001…
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Page 198
VALUMETRIC POSTON ASSY & CA-500 CYLINDER ASSY Code No. Drawing Description Qty per Unit 663-0164-1 VOLUMETRIC PISTON ASSY 663-0166-8 CYLINDER ASSY 663-0167-1 PISTON ASSY 663-0166-8 CYLINDER ASSY 442-3509-2 NIPPLE NO. 9 343-2466-0 O-RING NO.16 346-8215-2 SEAL TEFLON AR401-P3-XC CA-500 Series S/M… -
Page 199: Volumetric Mech. Assy
CA-500 Volumetric Mech. Assy CA-500 Series S/M A-1-22 Revised December 2001…
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Page 200
CA-500 Volumetric Mech. Assy Code No. Drawing Description Qty per Unit 663-0165-4 SYRINGE MOTOR ASSY 228-3753-3 PHOTO-INTERRUPTER LG-217D-3 342-1517-1 PULLEY NO.185 342-2776-6 PULLEY NO.143 CA-500 Series S/M A-1-23 Revised December 2001… -
Page 201: Operation Panel Assy (1/2
CA-500 Operation Panel Assy (1/2) CA-500 Series S/M A-1-24 Revised June 2003 ECR303C033…
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Page 202
228-9301-0 INVERTER INV-5 281-7226-1 PRINTER FTP-421MCL001 :PCB No.9303 developed for the CA-550/560 is compatible with all CA-500 series analyzers. Therefore, PCB No.9265 will be replaced by PCB No.9303 when current stock is depleted. TB200203 14 ECR303C033 ECR304C035 CA-500 Series S/M… -
Page 203: Operation Panel Assy (2/2
CA-500 Operation Panel Assy (2/2) CA-500 Series S/M A-1-26 Revised December 2001…
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Page 204
CA-500 Operation Panel Assy (2/2) Code No. Drawing Description Qty per Unit 663-0168-5 OPERATION PANEL ASSY 663-0170-3 OPERATION PANEL BASE ASSY 663-0171-7 EMERGENCY STOP SW ASSY 662-0228-4 PCB NO.9265 663-0169-9 VR ASSY CA-500 Series S/M A-1-27 Revised December 2001… -
Page 205: Rear Panel For Bottles
CA-500 Rear Panel for Bottles CA-500 Series S/M A-1-28 Revised December 2001…
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Page 206
CA-500 Rear Panel for Bottles Code No. Drawing Description Qty per Unit 442-1450-3 CONNECTING TUBE NO. 50 442-4003-7 NIPPLE NO.123 CA-500 Series S/M A-1-29 Revised December 2001… -
Page 207: Rinse Bottle Assy
CA-500 Rinse Bottle Assy CA-500 Waste Bottle Assy CA-500 Series S/M A-1-30 Revised December 2001…
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Page 208
BOTTLE TANK (WASTE 5L/RED) 663-0413-7 33-35# BOTTLE TANK (WASTE 5L/RED/EU/UK) 369-8602-9 INSTRUCTION LABEL-2 369-8603-2 INSTRUCTION LABEL-3 (JAPANESE) UNSALABLE 369-8016-8 CAUTION MARK NO. 16 * : For 117V # : For 220/240V TB200203 ECR301K074 ECR303F001 CA-500 Series S/M A-1-31 Revised June 2003… -
Page 209: Accessories
CA-500 Accessories CA-5H Z-Axis Position Adjustment Tool PM (Note) This tool is not included with CA-500 Accessories. ECR303C012 TB200408 CA-500 Series S/M A-1-32 Revised February 2004 TB200408…
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Page 210
663-0212-2 OPTION SAMPLE TUBE SPACER 10MM DIAMET # : Included in supply parts of CA-550/560. * : Included in supply parts of CA-510, 520, 530 and 540. CA-500 Z-Axis Position Adjustment Tool PM Code No. Drawing Description Qty per Unit… -
Page 212: Tubing Diagram
663-0165-4 SYRINGE MOTOR ASSY 663-0191-1 PRESSURE PUMP ASSY 663-0198-7 SOLENOID VALVE ASSY (VOLUMET.) 941-0131-3 SOLENOID VALVE NO.14D (PM) 663-0197-3 VACUUM PUMP ASSY 663-0209-1 RINSE BOTTLE ASSY CA-500 662-8222-1 WIRING CORD PD SIGNAL DW0590 CA-500 Series S/M A-1-35 Revised December 2001…
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Page 213: Pressure Chamber Assy
CA-500 Pressure Chamber Assy Code No. Drawing Description Qty per Unit 365-1333-3 SUPPORT NO.247 443-0823-8B CHAMBER NO.4 363-5015-0 FIXING MATERIAL NO.15 346-3939-1 O-RING P-39 — — — BOLT M8X10 346-3909-0 O-RING P-8 (NITRIL) CA-500 Series S/M A-1-36 Revised December 2001…
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Page 214: Panels
CA-500 Panels Code No. Drawing Description Qty per Unit 663-0373-5 TOP PANEL DM0930 663-0375-2 PANEL (R) DM0932 363-5015-0 PANEL (L) DM0931 324-9080-2 REAR PANEL DM0933 CA5H CA-500 Series S/M A-1-37 Revised December 2001…
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Page 215: Sampler
CA-500 Sampler Code No. Drawing Description Qty per Unit 324-9083-3 LOCK SPRING DM1298 324-9084-7 SS BASE PLATE DM1361 324-9085-1 SS ACTIARM DM1362 663-0175-1 SAMPLE TABLE BASE ASSY CA-500 Series S/M A-1-38 Revised February 2004 TB200408…
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Page 216
CA-500 Pressure Chamber Kit (OPTION) Code No. Drawing Description Qty per Unit 021-0011-0 PRESSURE CHAMBER KIT CA-5H 365-1333-3 SUPPORT NO.247 443-0823-8 CHAMBER NO. 4 363-5015-0 FIXING MATERIAL NO. 15 363-1597-8 STAY NO.11 443-2804-4 NON-RETURN VALVE MFP-6-V 346-3939-1 O-RING P-39 346-3909-0… -
Page 217: Recommended Parts
CA-500 RECOMMENDED PARTS PART NO. PART DESCRIPTION UNIT Q’TY <CLASS A> 663-0188-0 CATCHER ASSY 663-0162-3 COOLER ASSY 662-0221-9 PCB NO.6362 662-0287-4 PCB NO.6373 663-0184-5 PIPETTE CRUSH SENSOR ASSY 913-1091-3 STANDARD SCATTERING STICK SET <CLASS B> 424-9150-0 BOTTLE TANK-A (RINSE/BLUE) 424-9151-3…
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Page 218: Alphabetical Index
BOTTLE TANK-A (RINSE 2L/BLUE) 424-9150-0 A-1-31 BOTTLE TANK-A (WASTE 2L/RED) 424-9151-3 A-1-31 C ARM PLATE DM1221 324-9082-0 A-1-19 CA-500 PRESSURE CHAMBER ASSY A-1-5 CA-5H Z-AXIS POSITION ADJUSTMENT TOOL PM 031-0171-4 A-1-33 CATCH BOX DM1357 324-9078-4 A-1-17 CATCH HOLD PLATE DM1358…
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Page 219
LOCK SPRING DM1298 324-9083-3 A-1-38 MAIN UNIT FAN ASSY 663-0196-0 A-1-5 MAIN UNIT FAN ASSY 663-0196-0 A-1-35 MIXER MOTOR ASSY 663-0187-6 A-1-19 MIXER MOTOR ASSY 663-0187-6 A-1-35 NIPPLE NO. 9 442-3509-2 A-1-21 CA-500 Series S/M A-3-2 Revised February 2004 19 TB200408… -
Page 220
OPERATION PANEL ASSY 663-0168-5 A-1-25 OPERATION PANEL ASSY 663-0168-5 A-1-27 OPERATION PANEL BASE ASSY 663-0170-3 A-1-27 OPERATOR’S MANUAL CA-500 461-2047-7 A-1-33 OPERATORS MANUAL CA-500 (2) 461-2655-0 A-1-33 O-RING NO.16 343-2466-0 A-1-21 O-RING P- 8 (NITRIL) 346-3909-0 A-1-39 O-RING P-39 346-3939-1 A-1-36… -
Page 221
A-1-33 REAGENT RACK ASSY 663-0206-0 A-1-33 REAGENT STAGE ASSY 663-0202-5 A-1-3 REAR PANEL DM0933 CA5H 324-9080-2 A-1-37 RINSE BOTTLE ASSY CA-500 663-0209-1 A-1-35 RINSE BOTTLE ASSY CA-5H (2L) 663-0209-1 A-1-31 1-8* RINSE BOTTLE ASSY CA-5H (2L) 663-0209-1 A-1-33 RINSE BOTTLE ASSY CA-5H (2L/EU/UK) -
Page 222
6$¥ TRANSFORMER POWER ASSY (200V) 662-2208-7 A-1-5 TRAP CHAMBER COMPLETE 663-0211-9 A-1-33 TRAP CHAMBER PROCEDURE 461-9128-7 A-1-39 TRASH COVER CA-500 322-9151-5 A-1-9 TUBE SILICONE 1.5MMID X 6MMOD 442-5292-3 A-1-5 TUBE SILICONE 1/32″X3/32″F7391 442-5279-4 A-1-5 TUBE SILICONE 2 X 4MM SR-1554… -
Page 223
663-0182-8 A-1-17 Z AXIS MOTOR ASSY 663-0186-2 A-1-17 Z AXIS MOTOR ASSY 663-0186-2 A-1-35 Z1 SLIDER-C ASSY DU1469 663-0393-0 A-1-17 Z2 SLIDER-C ASSY DU1468 663-0394-3 A-1-17 ZSB REAR COVER 322-9152-9 A-1-17 CA-500 Series S/M A-3-6 Revised February 2004 19 TB200408… -
Page 224: Part No. Index
PART NO. INDEX PART NO. PART DESCRIPTION UNIT Q’TY PAGE CA-500 PRESSURE CHAMBER ASSY A-1-5 — — — BOLT M8X10 A-1-36 021-0011-0 PRESSURE CHAMBER KIT CA-5H A-1-39 031-0171-4 CA-5H Z-AXIS POSITION ADJUSTMENT TOOL PM A-1-33 228-3418-6 PHOTO SENSOR EE-SX670 A-1-3…
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Page 225
442-5305-4 TUBE SILICONE 2 X 4MM SR-1554 A-1-39 442-5315-1 TUBE SILICONE 2MMIDX5MMOD(CLR) A-1-5 442-5416-1 TUBE TEFLON 1.2MMID X 2.0MMOD A-1-5 442-5452-5 TUBE TEFLON 1.5MMID X 2.5MMOD A-1-5 442-5452-5 TUBE TEFLON 1.5MMID X 2.5MMOD A-1-5 CA-500 Series S/M A-4-2 Revised February 2004 TB200408… -
Page 226
443-2804-4 NON-RETURN VALVE MFP-6-V A-1-31 443-2804-4 NON-RETURN VALVE MFP-6-V A-1-31 443-2804-4 NON-RETURN VALVE MFP-6-V A-1-39 461-2047-7 OPERATOR’S MANUAL CA-500 A-1-33 461-2655-0 OPERATORS MANUAL CA-500 (2) A-1-33 461-9128-7 TRAP CHAMBER PROCEDURE A-1-39 541-1352-1 PUSH VIAL PV-10 A-1-33 662-0168-8 PCB NO. 6350 WITH ROM A-1-5 662-0217-3 PCB NO.2132 (STANDARD) -
Page 227
663-0185-9 Y AXIS MOTOR ASSY A-1-35 663-0186-2 Z AXIS MOTOR ASSY A-1-17 663-0186-2 Z AXIS MOTOR ASSY A-1-35 663-0187-6 MIXER MOTOR ASSY A-1-19 663-0187-6 MIXER MOTOR ASSY A-1-35 663-0188-0 CATCHER ASSY A-1-17 CA-500 Series S/M A-4-4 Revised February 2004 TB200408… -
Page 228
663-0207-3 REACTION TUBE TRASH BOX A-1-33 663-0209-1 RINSE BOTTLE ASSY CA-5H (2L) A-1-31 1-8* 663-0209-1 RINSE BOTTLE ASSY CA-5H (2L) A-1-33 663-0209-1 RINSE BOTTLE ASSY CA-500 A-1-35 663-0210-5 WASTE BOTTLE ASSY CA-5H (2L) A-1-31 21-26* 663-0210-5 WASTE BOTTLE ASSY CA-5H (2L) A-1-33… -
Page 229
664-0167-9 FILTER ASSY FOR RINSE BOTTLE A-1-31 833-3895-6 SAMPLE RACK NO. 3 W/HOLDER #55 A-1-33 913-1091-3 STANDARD SCATTERING STICK SET A-1-3 OPTION 921-0351-8 PAPER THERMAL F1-2 (5/BOX) A-1-33 941-0131-3 SOLENOID VALVE NO.14D (PM) A-1-35 CA-500 Series S/M A-4-6 Revised February 2004 TB200408… -
Page 230
Adjust LCD Contrast ……………………..B-10 Replenish Rinse Solution ……………………. B-11 B.10 Set Tube Trash Drawer……………………..B-13 B.11 Set Reagent Rack and Reaction Tube Rack ………………. B-13 B.12 Install Sampler with ID Bar Code Scanner (Option)…………….. B-14 CA-500 Series S/M Revised December 2001… -
Page 232
CA-500 Operator’s Manual 266-5293-0 Fuse 250V 3.15A No. 19195 (Europe) 266-5106-0 Fuse 250V 6.3A ST4-6.3A-N1 (N.Amer) 663-0213-6 Holder CA-500 (for 13 mm diameter tube) 369-5982-2 Indication Mark No. 954 (for Reagent Rack) 462-4842-7 Paper Thermal F1-2 (2/Pack) 265-4719-0 Power Cord 4622-007-0092 (Europe) 265-4723-5 Power Cord F1686 (U.K.) -
Page 233: Installation Space
• Be sure to place the rinse bottle and waste bottle on the base which the instrument is set. • Do not put them on the instrument, or there is a possibility the instrument may break down or fail to produce correct results. CA-500 Series S/M Revised December 2001…
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Page 234: Remove Shipping Clamps
Two fixing metals are retained with screws as shown. Loosen the screws and remove the metals. CAUTION: • Unless the fixing metals are removed, the instrument cannot operate. Figure B-2: Removing the Fixing Metals CA-500 Series S/M Revised December 2001…
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Page 235
Raise the sample probe by hand to a place where it is easy to operate. Remove the catcher retainer. Catcher Retainer Figure B-4: Removing the Catch Retainer CAUTION: • Unless the retainer is removed, the instrument cannot operate. CA-500 Series S/M Revised December 2001… -
Page 236: Attach Trap Chamber
• If hands should be contaminated with blood or the like, there is a hazard of being infected by pathogenic bacteria. Waste Vacuum Nipple (Green) Trap Chamber Nipple (Yellow) Figure B-5: Attaching the Trap Chamber CA-500 Series S/M Revised December 2001…
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Page 237: Connect Rinse Bottle And Waste Bottle
CAUTION: • Remove the rubber tube that locks the float switch in the rinse bottle and waste bottle. This rubber tube served to prevent vibration in transit. Rubber tube CA-500 Series S/M Revised December 2001…
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Page 238: Connect Power Cord And Connection Cord
NOTE: • For setting host computer interface parameters, refer to Operator’s Manual Chapter 10: Section 5.1: Host Computer. • The connection cord for the host computer is not included in the accessories. CA-500 Series S/M Revised December 2001…
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Page 239: Set Print Paper
Release the lock. Raise the lock lever to unlock. Lock Lever Figure B-10: Releasing the Lock Load a paper roll. Load a new print paper roll. Print Paper Figure B-11: Loading the Paper Roll CA-500 Series S/M Revised December 2001…
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Page 240
Pass the print paper as shown below and throw down the lock lever to lock. Lock Lever Figure B-12: Passing the Print Paper Feed a print paper. If power is turned ON, press [Sysmex] key, then [P. FEED] on the Sysmex Menu screen. Ready HC IP Replace Rack? YES! -
Page 241: Adjust Lcd Contrast
With the printer cover removed, LCD contrast can be adjusted using the contrast adjust dial located on the left of the printer. Turn the dial up for darker shade and turn it down for lighter shade. Contrast Adjust Dial Dark Light Figure B-14: Adjusting the LCD Contrast CA-500 Series S/M B-10 Revised December 2001…
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Page 242: Replenish Rinse Solution
Figure B-16: Supply Liquid Confirmation Screen Press [Set] key or [Cancel] key on the Supply Liquid Confirmation screen. [Set] key: Executes water supply. [Cancel]: Cancels water supply and returns the screen to the Root Menu. CA-500 Series S/M B-11 Revised December 2001…
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Page 243
Wa t e r s u p p ly ru n n in g C a n c e l Figure B-17: «Water supply running» Message Screen Water supply is completed. When water supply is over, the Special Operation Menu screen will return. CA-500 Series S/M B-12 Revised December 2001… -
Page 244: Set Tube Trash Drawer
Set the furnished reagent rack and reaction tube rack. Reaction Tube Rack Reagent Rack Figure B-19: Setting the Reagent Rack and Reaction Tube Rack Affix Indication Mark No. 954 on the reagent rack. CA-500 Series S/M B-13 Revised December 2001…
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Page 245: Install Sampler With Id Bar Code Scanner (Option
B.12 Install Sampler with ID Bar Code Scanner (Option) An optional Bar code Scanner is installed on the CA-510 or CA-530, as follows. Remove the left side panel of the CA-500 main unit. Loosen the screws as shown to remove the panel.
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Page 246
Mount the duct-attached slide rail to the sampler onto the side where the cable protrudes. All four screws should be temporarily tightened. Insert the cable from the sampler into the slide rail duct. CA-500 Series S/M B-15 Revised December 2001… -
Page 247
Push the sampler with ID bar code scanner in parallel. Push it in until the lock guide arms fit in the table lock of the CA-500 main unit. As you push it, the sampler will feel heavier, but keep pushing little by little. -
Page 248
With the sampler pulled out in parallel, fully tighten the screws that were temporarily tightened before. Make sure that the sampler with ID bar code scanner will slide in and out smoothly. Attach the left side panel of the CA-500 main unit. CA-500 Series S/M B-17… -
Page 249
Make sure that all labels are read without an error. Adjust the Pipette Position for the Sampler Perform pipette position adjustment. Refer to Service Manual 4.3.4 Position Adjustment Procedure of Pipette (“(1)blood 1”, “(2)blood 10” and “(3)blood stat”). CA-500 Series S/M B-18 Revised December 2001… -
Page 250
To Cover APPENDIX C DISASSEMBLY Detector Unit Assembly……………………..C-1 Cooler Unit Assembly……………………..C-3 Volumetric Unit Assembly ……………………..C-4 Drive Arm Assembly………………………C-5 Operation Panel Assembly…………………….C-8 CA-500 Series S/M Revised December 2001… -
Page 252: Appendix C Disassembly
Remove Detection Stage. (by removing 2 screws) CAUTION: Be careful not to hit the Detection Stage to the tip of the pipette. Detection Stage Reagent Stage Figure C-1: Removing Reagent Stage and Detection Stage CA-500 Series S/M Revised December 2001…
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Page 253
Remove two fixing screws (item 12) on the aluminum plate to remove the heater. PCB No.9259 PCB No.9259 Sarcon® Shield Case Thermal Sensor PCB No.2132 Slide Isolation Bush Shield Case Optical Block PCB No.2132 Figure C-2: Disassembling Detector Unit CA-500 Series S/M Revised December 2001… -
Page 254: Cooler Unit Assembly
Thermal Sensor is inserted in the Cooler Plate. (item 6) Cooler Fan is fixed by four fixing screws with spacers. Holding Plate Holding Sponge Cooler Plate Sarcon® Heat Isolation Sponge Pertier Sarcon® Heat Sink Slide Figure C-3: Disassembling Cooler Unit CA-500 Series S/M Revised December 2001…
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Page 255: Volumetric Unit Assembly
As for the adjustment of the tension between Idler and Pulley, adjust it at Pulley position. (Adjust the belt tension so that the belt is indented 4 mm when it is pushed at the center by a finger.) Pulley Idler Figure C-5: Adjusting Belt Tension CA-500 Series S/M Revised December 2001…
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Page 256: Drive Arm Assembly
Remove two fixing metals clamping the FPC (item 4), and remove the FPC from PCB No. 9260. Remove the screw fixing the X-axis shaft and loosen the screw of the aluminum plate on the left side. PCB No.9260 X-axis Shaft Figure C-7: Removing FPC CA-500 Series S/M Revised December 2001…
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Page 257
The linear slider and the bearing block on the lower side are included in the X-slider. (11) After removing six screws fixing the resin cover at the back side of the Z-axis base, you can access PCB No. 9264 (Z-Axis Home Position Sensor). Figure C-10: Accessing PCB No. 9264 CA-500 Series S/M Revised December 2001… -
Page 258
Catcher Rubber A Cord Holder Vibration Probe Cord Holder C Arm Tube Sensor Light Tube Sensor Light Shield Plate Shield Plate O ring C Arm SCL6-B Catcher SCL6-12 Spacer (Mixing Motor) Figure C-12: Catcher Unit Assembly CA-500 Series S/M Revised December 2001… -
Page 259: Operation Panel Assembly
Remove six screws on the back side of Operation Panel Assembly, and you can find Printer, LCD, VR Assembly and Emergency Stop Switch inside. PCB No. 9265 is fixed by four screws. Figure C-14: Operation Panel Assembly CA-500 Series S/M Revised December 2001…
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- Home
- Haemostasis
- CA-600
- More Information
The CA-600 system is a compact, fully automated coagulation analyser which utilises the proven optical detection technology and the same reagent system of Sysmex coagulation family analysers. It offers high performance automation for clotting assays in a true random access. Combining the simplicity of use and diagnostic power, the laboratory can be confident that they continuously stay ahead in haemostasis testing with the CA-600.
CA-600
Sysmex’s smallest fully automated haemostasis analyser that offers clotting detection principle.
The CA-600 system offers an economical, automated solution for low-medium volume laboratories to achieve analytical excellence, workflow efficiency and improved data management.
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The imprecision of manual coagulation testing is high, with coefficient of variation (CV) of greater than 20%; and duplicate measurement is thus recommended. With CA-600, fully automated coagulation analyser, the accuracy has greatly improved, attaining a CV of less than 5%, and as low as 1% for some tests.
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Based upon its predecessors, the proven optical based detection principle allows operator to visualise the clot formation, and together with its in-built checking algorithm, detect any unusual in-vitro clot formation to avoid the report of inaccurate results.
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Medical Technologists can now focus on higher value aspects of laboratory testing such as pre-analytics or post-analytics that require focused attention.
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Simultaneous analysis of up to 5 parameters and optimal throughput allow laboratories to perform routine and specialty testing in greater efficiency.
Excellent data management
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Sample barcode reader simplifies sample ID processing and enables security and integrity of patient records.
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Handheld 2D barcode reader simplifies the data entry process for ISI, control and calibrator values, lot numbers, and expiry information.
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Data up to 600 samples or 3000 tests can be stored onboard for easy retrieval for review.
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PT: Dade Innovin, Thromborel S
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APTT: Dade Actin, Dade Actin FS, Dade Actin FSL, Pathromtin SL
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Fibrinogen: Multifibren U, Dade Thrombin, Dade Fibrinogen Determination Reagent
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Thrombin Time: Test Thrombin, Thromboclotin
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Batroxobin Time: Batroxobin
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Factor Deficiency: Factor II, V, VII, VIII, IX, X, XI, XII
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Lupus Anticoagulant: LA1 screen, LA2 confirmation
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Protein C Pathway: ProC Global, Protein C Reagent
| Detection principles | Clotting: scattered light detection method |
| Detection channel/method | 4 LEDs with wavelength 660 nm for clotting assays |
| Parameters | 5-parameter random analysis simultaneously |
| Throughput | PT: 60 tests/hour PT/APTT/Fbg: 42 tests/hour |
| Sampling | Continuous-access 10 sample rack 1 dedicated STAT position |
| Reagent holder | 13 positions (with 4 cooled and 3 dedicated to diluents, buffers or cleaning reagents) |
| Reference curves | 1 reference curve per parameter 1 lot per parameter Maximum 14 parameters |
| Quality control | X-bar control, Levy-Jennings control 6 files with maximum 180 points each |
| Data storage | Up to 600 samples / maximum 3,000 tests |
| Printer | Internal printer |
| Dimensions (WxHxD)/weights | 566 x 490 x 490 mm, 42 kg (approximate) |
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+
Features & Benefits
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The CA-600 system offers an economical, automated solution for low-medium volume laboratories to achieve analytical excellence, workflow efficiency and improved data management.
-
The imprecision of manual coagulation testing is high, with coefficient of variation (CV) of greater than 20%; and duplicate measurement is thus recommended. With CA-600, fully automated coagulation analyser, the accuracy has greatly improved, attaining a CV of less than 5%, and as low as 1% for some tests.
-
Based upon its predecessors, the proven optical based detection principle allows operator to visualise the clot formation, and together with its in-built checking algorithm, detect any unusual in-vitro clot formation to avoid the report of inaccurate results.
-
Medical Technologists can now focus on higher value aspects of laboratory testing such as pre-analytics or post-analytics that require focused attention.
-
Simultaneous analysis of up to 5 parameters and optimal throughput allow laboratories to perform routine and specialty testing in greater efficiency.
Excellent data management
-
Sample barcode reader simplifies sample ID processing and enables security and integrity of patient records.
-
Handheld 2D barcode reader simplifies the data entry process for ISI, control and calibrator values, lot numbers, and expiry information.
-
Data up to 600 samples or 3000 tests can be stored onboard for easy retrieval for review.
-
-
+
Assay
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-
PT: Dade Innovin, Thromborel S
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APTT: Dade Actin, Dade Actin FS, Dade Actin FSL, Pathromtin SL
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Fibrinogen: Multifibren U, Dade Thrombin, Dade Fibrinogen Determination Reagent
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Thrombin Time: Test Thrombin, Thromboclotin
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Batroxobin Time: Batroxobin
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Factor Deficiency: Factor II, V, VII, VIII, IX, X, XI, XII
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Lupus Anticoagulant: LA1 screen, LA2 confirmation
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Protein C Pathway: ProC Global, Protein C Reagent
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Specifications
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Detection principles Clotting: scattered light detection method Detection channel/method 4 LEDs with wavelength 660 nm for clotting assays Parameters 5-parameter random
analysis simultaneouslyThroughput PT: 60 tests/hour
PT/APTT/Fbg: 42 tests/hourSampling Continuous-access 10 sample rack
1 dedicated STAT positionReagent holder 13 positions (with 4 cooled and 3 dedicated to diluents, buffers or cleaning reagents) Reference curves 1 reference curve per parameter
1 lot per parameter
Maximum 14 parametersQuality control X-bar control, Levy-Jennings control
6 files with maximum 180 points eachData storage Up to 600 samples / maximum 3,000 tests Printer Internal printer Dimensions (WxHxD)/weights 566 x 490 x 490 mm, 42 kg (approximate) -
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Documents
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